Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ril
Q-score: 0.551
Human RAD52 open ring conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8rj3
Q-score: 0.325
Liang CC, Greenhough LA, Masino L, Maslen S, Bajrami I, Tuppi M, Skehel M, Taylor IA, West SC
Nature (2024) [ Pubmed: 38658755 DOI: doi:10.1038/s41586-024-07347-7 ]
- Dna repair protein rad52 homolog (46 kDa, Protein from Homo sapiens)
- Open ring conformation of human rad52 (Complex from Homo sapiens)
Human RAD52 open ring - ssDNA complex
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 8rjw
Q-score: 0.512
Liang CC, Greenhough LA, Masino L, Maslen S, Bajrami I, Tuppi M, Skehel M, Taylor IA, West SC
Nature (2024) [ Pubmed: 38658755 DOI: doi:10.1038/s41586-024-07347-7 ]
- Ssdna (6 kDa, DNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Open ring conformation of human rad52 in complex with ssdna (Complex from Homo sapiens)
- Dna repair protein rad52 homolog (46 kDa, Protein from Homo sapiens)
Human Replication protein A (RPA; trimeric core) - ssDNA complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8rk2
Q-score: 0.436
Liang CC, Greenhough LA, Masino L, Maslen S, Bajrami I, Tuppi M, Skehel M, Taylor IA, West SC
Nature (2024) [ Pubmed: 38658755 DOI: doi:10.1038/s41586-024-07347-7 ]
- Replication protein a 14 kda subunit (13 kDa, Protein from Homo sapiens)
- Replication protein a 32 kda subunit (29 kDa, Protein from Homo sapiens)
- Replication protein a 70 kda dna-binding subunit, n-terminally processed (68 kDa, Protein from Homo sapiens)
- Open ring conformation of human rad52 in complex with ssdna (Complex from Homo sapiens)
Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
Greenhough LA, Liang CC, Belan O, Kunzelmann S, Maslen S, Rodrigo-Brenni MC, Anand R, Skehel M, Boulton SJ, West SC
Nature (2023) 619 pp. 650-657 [ DOI: doi:10.1038/s41586-023-06179-1 Pubmed: 37344587 ]
Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ouy
Q-score: 0.523
Greenhough LA, Liang CC, Belan O, Kunzelmann S, Maslen S, Rodrigo-Brenni MC, Anand R, Skehel M, Boulton SJ, West SC
Nature (2023) 619 pp. 650-657 [ DOI: doi:10.1038/s41586-023-06179-1 Pubmed: 37344587 ]
- Dna repair protein rad51 homolog 4 (35 kDa, Protein from Homo sapiens)
- Dna repair protein xrcc2 (31 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Rad51b-rad51c-rad51d-xrcc2 (bcdx2) (Complex from Homo sapiens)
- Dna repair protein rad51 homolog 2 (38 kDa, Protein from Homo sapiens)
- Dna repair protein rad51 homolog 3 (42 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 2.2 A resolution
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8ouz
Q-score: 0.625
Greenhough LA, Liang CC, Belan O, Kunzelmann S, Maslen S, Rodrigo-Brenni MC, Anand R, Skehel M, Boulton SJ, West SC
Nature (2023) 619 pp. 650-657 [ DOI: doi:10.1038/s41586-023-06179-1 Pubmed: 37344587 ]
- Dna repair protein rad51 homolog 4 (35 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Rad51b-rad51c-rad51d-xrcc2 (bcdx2) (Complex from Homo sapiens)
- Dna repair protein xrcc2 (31 kDa, Protein from Homo sapiens)
- Dna repair protein rad51 homolog 2 (38 kDa, Protein from Homo sapiens)
- Dna repair protein rad51 homolog 3 (42 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)